Indriya-sthana, the fifth section of the Caraka‑Saṃhitā—an early classical Ayurvedic compendium redacted by Charaka from older teachings (early centuries CE)—is a masterclass in bedside prognosis. It teaches clinicians to read the body and mind through the senses: sight, touch, taste, smell, hearing and mental observation. The chapter catalogs signs of recovery or decline, links sensory findings to dosha dynamics and disease stages, and stresses trained perception, timing, and ethical judgment. Rooted in empirical clinical lore, Indriya‑sthana’s emphasis on close observation, low‑tech diagnostics and humane prognostication remains strikingly relevant to modern primary care, palliative decision‑making, and integrative medicine.