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Astanga Hrudaya

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असाध्या सन्निपातेन खलतिः पलितानि च । शरीरपरिणामोत्थान्यपेक्षन्ते रसायनम् ॥ ३२ ॥

Khalati and Palita caused by Sannipata are incurable. Those (Khalati and Palita) which are due to changes in the body (metabolism, old age, effects of diseases etc.) require Rasayana (rejuvenator therapy).

english translation