Astanga Hrudaya

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आधिभिर्चित्तविभ्रंशाद्विषेणोपविषेण च । एभिर्हि हीनसत्त्वस्य हृदि दोषाः प्रदूषिताः ॥ ४ ॥

due to mental distress leading to loss of balance of mind, and by the effect of strong poisons or semi-poisons (upavisha)—by these causes, the doshas get highly vitiated in the heart of a person of feeble mind;

english translation

AdhibhircittavibhraMzAdviSeNopaviSeNa ca । ebhirhi hInasattvasya hRdi doSAH pradUSitAH ॥ 4 ॥

hk transliteration by Sanscript