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Astanga Hrudaya

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अन्तस्तस्यास्रवन् दोषः सूक्ष्मां सञ्जनयेद्गतिम् । पूयं मुहुः सा स्रवति त्वङ्मांसास्थिप्रभेदिनी ॥ ३० ॥

in such a patient the doshas remaining inside, not coming out, create minute fissures, pus comes out of these often, the skin, muscles and bones get destroyed.

english translation

Chapter 21

Verse 31