Astanga Hrudaya
विपरीतगुणेच्छा च कोपस्तून्मार्गगामिता। लिङ्गानां दर्शनं स्वेषामस्वास्थ्यं रोगसम्भवः॥२३॥
It is a self defense mechanism of the body to avoid further increase of Dosha, which may lead to disease. Kopa- Kopa – suggests further increase of Dosha and overflow of increased Dosha into other body channels. It causes appearance of symptoms of increased Dosha, leading to onset of disease process. The premonitory symptoms of the disease can be observed at this stage.
english translation
viparItaguNecchA ca kopastUnmArgagAmitA। liGgAnAM darzanaM sveSAmasvAsthyaM rogasambhavaH॥23॥
hk transliteration by Sanscript