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Astanga Hrudaya

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आखोरिव विषं क्रुद्धं कृत्स्नं देहं विधावति । त्वङ्मांसाश्रयमुत्तानं तत्पूर्वं जायते ततः ॥ ८ ॥

then spreads to the entire body like the poison of rat bite, (slowly and steadily over long periods of time) residing in the skin and muscles, it starts first as uttana type – superficial, and then,

english translation