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Astanga Hrudaya

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कुपितः कुरुते रोगान् कृच्छ्रान् पक्वाशयाश्रयान् । मूत्रशुक्रप्रदोषार्शोगुदभ्रंशादिकान् बहून् ॥ २८ ॥

when aggravated by the above causative factors, Apana Vata causes it gives to many disease that are difficult to cure, of the large intestines, disorders of urine and semen, piles, prolapse of the rectum etc.

english translation