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Charak Samhita

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रसो निपाते द्रव्याणां, विपाकः कर्मनिष्ठया। वीर्यं यावदधीवासान्निपाताच्चोपलभ्यते ॥६६॥

[Characteristics of rasa, veerya, vipaka] Rasa is perceived by its contact with the body (particularly tongue). Vipaka is perceived by (observing) the final effect (on body) and veerya is comprehended (by the action exerted) during the period from administration till excretion (of the drug).

english translation