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Astanga Hrudaya

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siva.sh/astanga-hrudaya/uttara-sthana/36/3

विषं दर्वीकरादीनां क्रमाद्वातादिकोपनम् । तारुण्यमध्यवृद्धत्वे वृष्टिशीतातपेषु च ॥ ३ ॥

these cause aggravation of Vata etc. respectively. They (darvikara etc.) become loaded with more poison during their youth, middle age and old age, rainy, cold and summer seasons respectively;

english translation

Chapter 36

Verse 4