Astanga Hrudaya
कफोद्रेके गदेऽनन्नं बलिनो रोगरोगिणोः। अन्नादौ विगुणेऽपाने, समाने मध्य इष्यते॥३८॥
Medicines should be administered, 1. Ananna – on empty stomach – For diseases arising from increase of Kapha, which are severe and for persons who are strong, the time of administration of medicine shall be when there is no food- in the stomach ;
english translation