Astanga Hrudaya

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रिष्टोक्तं यच्च यच्चास्थिमज्जशुक्रसमाश्रयम् । याप्यं मेदोगतं कृच्छ्रं पित्तद्वन्द्वास्रमांसगम् ॥ ३२ ॥

which has been described in rista, chapter 5 of sarirasthana and that which has localised in the bone, bone marrow and semen. Skin diseases afflicting fat tissue is Yapya – requires treatment for lifetime, that caused by pitta, in combination with any other dosha and localised in blood and muscle is difficult to cure

english translation

riSToktaM yacca yaccAsthimajjazukrasamAzrayam । yApyaM medogataM kRcchraM pittadvandvAsramAMsagam ॥ 32 ॥

hk transliteration by Sanscript