Charak Samhita

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चिन्ताकामभयक्रोधशोकोद्वेगादिभिस्तथा| मनस्यभिहते नॄणामपस्मारः प्रवर्तते ||५||

sanskrit

The heart (site of consciousness) is obscured by aggravated doshas; and Mind is distressed or annihilated by (affliction of negative emotions like) worry, passion, fright, anger, grief, anxiety etc.

english translation

cintAkAmabhayakrodhazokodvegAdibhistathA| manasyabhihate nRRNAmapasmAraH pravartate ||5||

hk transliteration