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Brihat Parashara Hora Shastra

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पाकेशाक्रान्तराशौ वा बाधास्थाने शुभेतरे । स्थिते सति महाशोको बन्धनव्यसनामयाः ॥ २१॥

If there is a malefic in the Bhava, occupied by its Lord, or in Badhak Bhava of that Rāśi, there will be occasions of great sorrow, imprisonment and diseases during the Dasha.

english translation