Astanga Hrudaya
हरेद्बहूंश्चलान् दोषानल्पानल्पान् पुनःपुनः। दुर्बलस्य मृदुद्रव्यैरल्पान् संशमयेत्तु तान्॥५१॥
Large dose given once creates doubt of death; The drug in small and repeated doses will eliminate the circulating Doshas little by little; in a weak person, little quantity of Doshas should only be mitigated by mild drugs, they need not be expelled out by purification therapies .
english translation
haredbahUMzcalAn doSAnalpAnalpAn punaHpunaH। durbalasya mRdudravyairalpAn saMzamayettu tAn॥51॥
hk transliteration by Sanscript