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Charak Samhita

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सम्यग्विपाकवीर्याणि प्रभावश्चाप्युदाहृतः। किञ्चिद्रसेन कुरुते कर्म वीर्येण चापरम् ॥७१॥

Thus, vipaka, veerya and prabhava are explained well. Some drug acts by (means of) rasa, other by veerya and other by guna, vipaka or prabhava.

english translation

Chapter 26

Verse 72