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Charak Samhita

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मेदस्यतीव संवृद्धे सहसैवानिलादयः। विकारान् दारुणान् कृत्वा नाशयन्त्याशु जीवितम् ॥८॥

These factors blight an obese person as wildfire destroys a forest. As the body gains excessive fat, vitiated dosha suddenly cause severe diseases resulting in rapid deterioration of life.

english translation