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Charak Samhita

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एतावुपद्रवकरौ विशेषादग्निमारुतौ। एतौ हि दहतः स्थूलं वनदावो वनं यथा ॥७॥

Agni (pitta component responsible for digestion) and vata are the two most troublesome factors from the standpoint of obesity.

english translation

Chapter 21

Verse 8