Charak Samhita

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चिरजातकठिनबलेषु व्याधिषु तीक्ष्णा विपर्यये मृदवः| सप्रतिवापकषाया योज्यास्त्वनुवासननिरूहाः||१७||

In disease conditions which are chronic, obstinate and severe, anuvasana and niruha basti prepared with strong decoction and later added with strong ingredients should be used. While in opposite disease conditions (which are mild and of recent origin) ingredients having mild effects should be used.

english translation

cirajAtakaThinabaleSu vyAdhiSu tIkSNA viparyaye mRdavaH| saprativApakaSAyA yojyAstvanuvAsananirUhAH||17||

hk transliteration by Sanscript