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Charak Samhita

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नासाध्यः साध्यतां याति साध्यो याति त्वसाध्यताम् । पादापचाराद्दैवाद्वा यान्ति भावान्तरं गदाः ॥३५॥

The easily curable kinds may also become difficult to cure, if not incurable, while diseases that are difficult to cure may become palliable and palliable variety may become incurable.

english translation