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Charak Samhita

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साध्यानामपि ह्युपेक्ष्यमाणानां त्वङ्मांसशोणितलसीकाकोथक्लेदसंस्वेदजाः क्रिमयोऽभिमूर्च्छन्ति; ते भक्षयन्तस्त्वगादीन् दोषाः पुनर्दूषयन्त इमानुपद्रवान् पृथक् पृथगुत्पादयन्ति- तत्र वातः श्यावारुणवर्णंपरुषतामपि च रौक्ष्यशूलशोषतोदवेपथुहर्षसङ्कोचायासस्तम्भसुप्तिभेदभङ्गान्, पित्तं दाहस्वेदक्लेदकोथस्रावपाकरागान्, श्लेष्मा त्वस्य श्वैत्यशैत्यकण्डूस्थैर्यगौरवोत्सेधोपस्नेहोपलेपान्, क्रिमयस्तु त्वगादींश्चतुरःसिराः स्नायूश्चास्थीन्यपि च तरुणान्याददते ॥१०॥

[Complications of kushtha] If the curable diseases are neglected (not treated), then they are also afflicted with putrefaction of skin, muscle tissue, blood, lymph and swedaja krimi (maggots or micro-organisms). The krimi get nourishment from the decayed skin etc. and further vitiate doshas leading to variety of complications corresponding to individual doshas as follows: 1. Due to vata, blackish and downy red discoloration appears, roughness, dryness, piercing pain, emaciation (atrophy), pricking pain, tremors, horripilation, constriction, exhaustion, stiffness, numbness, ulceration and fissures; 2. Pitta causes burning sensation, sweating, moistening, putrefaction, discharge, suppuration and redness; 3. Kapha causes whiteness, coldness, itching, immobility, heaviness, protuberance, unctuousness and coating, maggots eat up the skin etc. (skin, flesh, blood, lymph) vessels, ligaments and cartilages.

english translation