नातिग्लानिकरं पायौ हृदये न च रुक्करम्| अन्तराशयमक्षिण्वन् कृत्स्नं दोषं निरस्यति||५२||
[Tikshna (sharp acting)] The action of the drug which has easy expulsion without any difficulties, quick in action, immediate effect, forceful & unimpeded evacuation, without producing fatigue & painful sensation in the chest, anus, does not produce any discomfort to inner organs,
विरेचनं निरूहो वा तत्तीक्ष्णमिति निर्दिशेत्| जलाग्निकीटैरस्पृष्टं देशकालगुणान्वितम्||५३||
expulses the morbid doshas completely are said to be tikshna category of therapeutic emesis, purgation & medicated enema. The drugs which are not deteriorated by water (moisture), fire (heat & temperature), insects (microorganisms), collected from an ideal land, in specific season, with utmost required properties,
administered in slightly higher doses, potencified by triturating with the similar quality drugs when used in the person underwent proper snehana & swedana therapy will produce tikshna action.
किञ्चिदेभिर्गुणैर्हीनं पूर्वोक्तैर्मात्रया तथा| स्निग्धस्विन्नस्य वा सम्यङ्मध्यं भवति भेषजम्||५५||
[Madhyama (medium)] The drugs with slightly less quality than above mentioned characteristic features used in medium dosage will produce medium action in the person who underwent proper snehana & swedana and are called as madhyama.