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विरेचनं निरूहो वा तत्तीक्ष्णमिति निर्दिशेत्| जलाग्निकीटैरस्पृष्टं देशकालगुणान्वितम्||५३||

expulses the morbid doshas completely are said to be tikshna category of therapeutic emesis, purgation & medicated enema. The drugs which are not deteriorated by water (moisture), fire (heat & temperature), insects (microorganisms), collected from an ideal land, in specific season, with utmost required properties,

english translation

virecanaM nirUho vA tattIkSNamiti nirdizet| jalAgnikITairaspRSTaM dezakAlaguNAnvitam||53||

hk transliteration by Sanscript