Charak Samhita

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तानि तु द्रव्याणि देश-काल-गुण-भाजन-सम्पद्वीर्यबलाधानात् क्रियासमर्थतमानि भवन्ति||७||

These drugs are the most potent when they are exposed to the most suitable of place, time, properties and containers.

english translation

tAni tu dravyANi deza-kAla-guNa-bhAjana-sampadvIryabalAdhAnAt kriyAsamarthatamAni bhavanti||7||

hk transliteration by Sanscript