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Charak Samhita

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त्रयः प्रकुपिता यस्य दोषाः कष्टाभिलक्षिताः । कृशस्य बलहीनस्य नास्ति तस्य चिकित्सितम् ॥१७॥

A patient who is having thin stature, wasting of muscles, with Horripilation, colloidal or thick urine, with edema, cough, and fever, should be avoided by physician.

english translation