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Charak Samhita

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अयोगमतियोगं वा शरीरे मतिमान् भिषक्। खादीनां युगपद्दृष्ट्वा भेषजं नावचारयेत् ॥२२॥

[Physician's ethical code to abstain from prescription] A wise physician should abstain from treating a patient when he observes that the patient’s body is simultaneously responding both excessively and deficiently to sensory stimuli.

english translation