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Charak Samhita

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सप्त च्छिद्राणि शिरसि द्वे चाधः,साध्यमूर्ध्वगम्। याप्यं त्वधोगं, मार्गौ तु साध्यं प्रपद्यते ॥१६॥

That coming from upper passages is curable, the one coming downwards is palliable and that which comes both ways is incurable.

english translation