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Charak Samhita

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जायते तेन सोऽत्यर्थं क्षीणधातुः सुदुर्बलः । विवर्णो दुर्बलो दीनः क्षिप्रं व्याधिमथाश्नुते ॥१८०॥

Eventually, the person keeps on aging with deep debility of dhatu, weakness, loss of complexion, with poor energy, easily caught by the diseases.

english translation