Charak Samhita

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विषमो धातुवैषम्यं करोति विषमं पचन्| तीक्ष्णो मन्देन्धनो धातून् विशोषयति पावकः||५०||

sanskrit

[Effects of Vishamagni (irregular agni)and tikshanagni( excessive agni)] The vishamagni (improper agni) causes irregularity in digestion and therefore defective formation of dhatu takes place whereas, tikshanagni (excessive agni) when associated with little quantity of fuel (in the form of food) causes depletion of dhatu (tissue elements)

english translation

viSamo dhAtuvaiSamyaM karoti viSamaM pacan| tIkSNo mandendhano dhAtUn vizoSayati pAvakaH||50||

hk transliteration by Sanscript