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Charak Samhita

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दोषाणामपि चैवं स्यादेकदेशप्रकोपणम् । इति भौतिकधात्वन्नपक्तॄणां कर्म भाषितम्॥३८।

This principle is applicable even in case of dosha, where ekadesha prakopa (abnormal increase at a local site) occurs Thus ends the description of the physiological functions of bhutagni, dhatvagni and jatharagni.

english translation