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Charak Samhita

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क्षिप्यमाणः खवैगुण्याद्रसः सज्जति यत्र सः। करोति विकृतिं तत्र खे वर्षमिव तोयदः॥३७॥

[Significance of Kha-Vaigunya (abnormality in body system) in causing disease state] Wherever the rasa experiences obstacle due to abnormality in srotas, rasa readily produces disease in that very same location. This process is comparable with that of the clouds producing rainfall in a localized region that is favorable for rainfall

english translation