Charak Samhita

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तथायुक्ते हि समुदये समुदायप्रभावतत्त्वमेवमेवोपलभ्य ततो द्रव्यविकारप्रभावतत्त्वं व्यवस्येत् ॥११॥

In such cases, the effect of the dravya or the disease is ascertained on the basis of their cumulative action.

english translation

tathAyukte hi samudaye samudAyaprabhAvatattvamevamevopalabhya tato dravyavikAraprabhAvatattvaM vyavasyet ॥11॥

hk transliteration by Sanscript