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Charak Samhita

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इन्द्रियाणि समाश्रित्य प्रकुप्यन्ति यदा मलाः। उपघातोपतापाभ्यां योजयन्तीन्द्रियाणि ते ॥२०॥

[Disease of sense organs] When the dosha get vitiated in sense organs, they either cause impairment or deformity of the respective sense organ.

english translation