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Charak Samhita

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न चास्य जायते गर्भः पतति प्रस्रवत्यपि। शुक्रं हि दुष्टं सापत्यं सदारं बाधते नरम् ॥१९॥

There could be cases of no conception, or there will be spontaneous abortion. Thus, abnormalities of shukra dhatu result in misery for the individual as well as his family.

english translation