Charak Samhita

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अमनोरुचितं यच्च हृद्विरुद्धं तदुच्यते। सम्पद्विरुद्धं तद्विद्यादसञ्जातरसं तु यत् ॥१००॥

Antagonism in terms of palatability is taking of unlikeable things. Antagonism in terms of richness (of qualities) is that if there is immature, overmature or damaged rasa in a substance.

english translation

amanorucitaM yacca hRdviruddhaM taducyate। sampadviruddhaM tadvidyAdasaJjAtarasaM tu yat ॥100॥

hk transliteration by Sanscript