Charak Samhita

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अमनोरुचितं यच्च हृद्विरुद्धं तदुच्यते| सम्पद्विरुद्धं तद्विद्यादसञ्जातरसं तु यत् ||१००||

sanskrit

Antagonism in terms of palatability is taking of unlikeable things. Antagonism in terms of richness (of qualities) is that if there is immature, overmature or damaged rasa in a substance.

english translation

amanorucitaM yacca hRdviruddhaM taducyate| sampadviruddhaM tadvidyAdasaJjAtarasaM tu yat ||100||

hk transliteration