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Charak Samhita

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रजस्तमोभ्यां तु मनः परीतं सत्त्वसञ्ज्ञकम्। शरीरस्य समुत्पत्तौ विकाराणां च कारणम् ॥११॥

The manas(mind), influenced by rajas and tamas, which is also called sattva, is the real cause of the origin of the body and its afflictions, both."

english translation