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Charak Samhita

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सर्वेऽपि तु खल्वेतेऽभिप्रवृद्धाश्चत्वारो रोगाः परस्परमनुबध्नन्ति, न चान्योन्येन सह सन्देहमापद्यन्ते ॥६॥

All these four types of diseases when aggravated get transform into each other to share common symptoms. Even then, the distinctive features of each one of these diseases are too clearly manifested to allow any confusion.

english translation