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Charak Samhita

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संयोगे च विभागे च कारणं द्रव्यमाश्रितम्। कर्तव्यस्य क्रिया कर्म कर्म नान्यदपेक्षते ॥५२॥

Karma (action): The causative factor in conjunction and disjunction is located in dravya and performance of the activities to be done (as intended by the doer) is karma (action). Karma does not depend on any other factor (to produce the activities).

english translation