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Charak Samhita

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त्रिचतुःपञ्चसंसर्गानेवमेव विकल्पयेत्। युक्तिश्चैषातिसारोक्ता सर्वरोगेष्वपि स्मृता॥३४॥

[Treatment for conditions due to samsarga (combination of dosha)] Similarly a plan may be designed in cases of morbid combinations of three, four or five components. This planning for atisara is applicable in all disease conditions.

english translation