मिथ्यातिहीनलिङ्गाश्च वर्षान्ता रोगहेतवः| जीर्णभुक्तप्रजीर्णान्नकालाकालस्थितिश्च [१] या ||१११||
This category includes causative factors of diseases marked by wrong manifestation, over manifestation and under manifestation of their symptoms during seasons ending with the rains; during various stages of digestion viz. time of final digestion, time of intake of food and time of initial digestion;
पूर्वमध्यापराह्णाश्च रात्र्या यामास्त्रयश्च ये| एषु कालेषु नियता ये रोगास्ते च कालजाः ||११२||
during different times of the day, viz. forenoon, mid-day and afternoon and during different hours of the night, viz. pre-midnight, midnight and post mid night. Diseases which as a rule manifest themselves during these times are also known as kalaja diseases.
Diseases like anyedyushka (quotidian fever which occurs at a fixed time every day), dvyahagrahi (reverse quotidian fever), tritiyaka (tertian fever which occurs at an interval of one day) and chaturthaka (quartan fever which occurs at an interval of two days) manifest themselves at fixed hours in as much as they get strength only at such hours.
एते चान्ये [६] च ये केचित् कालजा विविधा गदाः| अनागते चिकित्स्यास्ते बलकालौ विजानता ||११४||
A physician acquainted with the knowledge of dosha bala and kala bala should treat this and other similar diseases prior to their actual manifestations.
The diseases arising out of temporal factors that bring about old age and death are to be considered as natural ones, which affect everyone, and these such natural manifestations are irremediable.