Charak Samhita

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स्वरसैस्तुल्यवीर्यैर्वा तस्माद्द्रव्याणि भावयेत्। अल्पस्यापि महार्थत्वं प्रभूतस्याल्पकर्मताम्॥४८॥

This method also potentiates the multidimensional action of the preparation. By the combination and separation of drugs, kala (time), sanskara (processings), & yukti (proper planning) one can modify the potency of medicaments.

english translation

svarasaistulyavIryairvA tasmAddravyANi bhAvayet। alpasyApi mahArthatvaM prabhUtasyAlpakarmatAm॥48॥

hk transliteration by Sanscript