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Charak Samhita

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संसृष्टा व्याधयो यस्य प्रतिलोमानुलोमगाः। व्यापन्ना ग्रहणी प्रायः सोऽर्धमासं न जीवति ॥२०॥

The patient afflicted with multiple doshas having movements in upward, downward both directions along with disordered grahani(Duodenum and Small intestine) cannot survive for longer than for a fortnight.

english translation