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Charak Samhita

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आनाहश्चातिसारश्च यमेतौ दुर्बलं नरम्। व्याधितं विशतो रोगौ दुर्लभं तस्य जीवितम् ॥८॥

[Poor prognosis in anaha] Further, when gambheera hikka (hiccups with deeper pathology) is associated with anaha (distended abdomen) and atisara (diarrhea), both in a weak person is most difficult to treat and the person’s life is in danger.

english translation