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Charak Samhita

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आहारमुपयुञ्जानो भिषजा सूपकल्पितम्। यः फलं तस्य नाप्नोति दुर्लभं तस्य जीवितम् ॥८॥

If a diet prepared and administered as per advice of physician, not giving desired effect, the patient hardly survives.

english translation