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Charak Samhita

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सर्वैरर्धैस्त्रिभिर्वाऽपि लिङ्गैर्मांसबलक्षये। युक्तो वर्ज्यश्चिकित्स्यस्तु सर्वरूपोऽप्यतोऽन्यथा ॥४७॥

With eleven, six or even three of the symptoms, a patient is incurable if he is losing mamsa (flesh tissues) and strength, but he is curable if he is behaving otherwise in spite of showing all the symptoms.

english translation