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Charak Samhita

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द्वौ कालौ दन्तपवनं भक्षयेन्मुखधावनम्। तद्वत् प्रक्षालयेदास्यं धारयेत् कवलग्रहान् ॥१३५॥

These are as follows: 1. Tooth-twigs should be used twice a day for brushing one’s teeth and then use mukhadhavana (drugs chewed for alleviating vitiated doshas in the mouth).

english translation