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Charak Samhita

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गुल्मो यद्यनिलादीनां कृते सम्यग्भिषग्जिते। न प्रशाम्यति रक्तस्य सोऽवसेकात् प्रशाम्यति ॥३२॥

[Blood-letting in vata gulma] If gulma does not subside even after proper treatment of vata etc. mentioned above then bloodletting is advised to cure it

english translation