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Charak Samhita

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यद्विदोषानुगं यद्वा शान्तं शान्तं प्रकुप्यति। मार्गान्मार्गं चरेद्यद्वा याप्यं पित्तमसृक् चतत् ॥२१॥

That raktapitta is palliable which is associated with two doshas, which aggravates again and again after subsiding and shifts from one passage to another.

english translation