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नाल्पं हन्त्यौषधं व्याधिं यथाऽऽपोऽल्पा महानलम् | दोषवच्चातिमात्रं स्यात्सस्यस्यात्युदकं यथा ||३१३||

[Importance of proper dosage] As very small quantity of water cannot extinguish big fire, similarly small doses (insufficient dose) of medicine cannot inhibit or treat disease.

english translation

nAlpaM hantyauSadhaM vyAdhiM yathA''po'lpA mahAnalam | doSavaccAtimAtraM syAtsasyasyAtyudakaM yathA ||313||

hk transliteration by Sanscript