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Charak Samhita

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ज्वरप्रत्यात्मिकं लिङ्गं सन्तापो देहमानसः। ज्वरेणाविशता भूतं न हि किञ्चिन्न तप्यते ॥३१॥

[Cardinal feature] The clinical features invariably associated with jwara are the feeling of heat or increased body temperature and discomfort in body and mind. Jwara afflicts the whole body including mind and sensory organs in all living beings.

english translation