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Charak Samhita

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श्वयथुर्भृशरुक् [२] तोदस्ताम्रश्चिमिचिमायते । स्निग्धरूक्षैः शमं नैति कण्डूक्लेदान्वितोऽसृजि [३] ॥२७॥

If rakta is predominant, there is swelling, severe pain of pricking nature, tingling sensation, colour of part of skin becomes coppery, not diminished by application of either unctuous or dry substances associated with itching and moistening over the part.

english translation